SpectraPor®
Tube-A-Lyzer
Tube-A-Lyzer® is a ready-to-use device that combines single-use convenience with the efficiency of dynamic dialysis to significantly improve dialysis efficiency and can reduce time from days to hours. The unique two chamber-device features a membrane defined sample chamber with a port for easy sample loading and recovery; surrounded by a flow-through buffer chamber for continuous and gentle dialysis. Compared to traditional-static dialysis, the continuous buffer flow increases the mass transfer rate across the semi-permeable membrane to achieve a higher exchange rate and purity in less time.
The Tube-A-Lyzer® easily mounts on a standard lab stand with a tube clamp and connects to a separate buffer source that is continuously pumped in either single-pass or recirculation mode. Two units can be coupled for operating in parallel. (Stand, pump, pump tubing and bracket sold separately).
Available in 2 sample volume sizes (8-10 ml and 25-30 ml) and made with with high purity Biotech Grade Cellulose Ester (CE) membrane in 6 MWCOs ranging from 0.1-100 kD (refer to the Chemical Compatibility table).
Features
2 sample volume sizes (8-10 ml & 25-30 ml)
Easy access port for sample loading, recovery & testing
Biotech CE membrane in 6 concise MWCO’s (0.1 – 100 kD)
Flow through buffer chamber for dynamic dialysis
Coupling for parallel operation or split-flow
Typical Dialysis Applications for Tube-A-Lyzer® Dialysis Devices
Gentle purification of labile proteins and conjugates
Isolation of delicate macromolecules
Biopolymer purification and removal of monomers
Buffer exchange for protein refolding
Enzyme activity and ligand binding studies
UNIQUE DESIGN
Tubular membrane allows for maximum surface area and minimum volume uptake & dilution. Float ring ensures buoyancy and vertical orientation.
EASY TO USE
Screw-on cap and pipette provides easy and safe sample loading and in-process testing with no dangerous needles.
TOTAL SAMPLE RECOVERY
Cylindrical shape provides open access for 95-98% sample volume recovery.
BROAD MWCO RANGE
9 MWCOs from 0.1 - 1,000 kD for all dialysis applications from small peptides to large nanoparticles.
HIGH PURITY
Achieve 98% sample purity with Biotech CE membrane, no heavy metal and sulfides.
