SpectraPor®
Tube-A-Lyzer 

Tube-A-Lyzer® is a ready-to-use device that combines single-use convenience with the efficiency of dynamic dialysis to significantly improve dialysis efficiency and can reduce time from days to hours. The unique two chamber-device features a membrane defined sample chamber with a port for easy sample loading and recovery; surrounded by a flow-through buffer chamber for continuous and gentle dialysis. Compared to traditional-static dialysis, the continuous buffer flow increases the mass transfer rate across the semi-permeable membrane to achieve a higher exchange rate and purity in less time.

The Tube-A-Lyzer® easily mounts on a standard lab stand with a tube clamp and connects to a separate buffer source that is continuously pumped in either single-pass or recirculation mode. Two units can be coupled for operating in parallel. (Stand, pump, pump tubing and bracket sold separately).

Available in 2 sample volume sizes (8-10 ml and 25-30 ml) and made with with high purity Biotech Grade Cellulose Ester (CE) membrane in 6 MWCOs ranging from 0.1-100 kD (refer to the Chemical Compatibility table).

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Features

2 sample volume sizes (8-10 ml & 25-30 ml)
Easy access port for sample loading, recovery & testing
Biotech CE membrane in 6 concise MWCO’s (0.1 – 100 kD)
Flow through buffer chamber for dynamic dialysis
Coupling for parallel operation or split-flow

Typical Dialysis Applications for Tube-A-Lyzer® Dialysis Devices

Gentle purification of labile proteins and conjugates
Isolation of delicate macromolecules
Biopolymer purification and removal of monomers
Buffer exchange for protein refolding
Enzyme activity and ligand binding studies
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UNIQUE DESIGN
Tubular membrane allows for maximum surface area and minimum volume uptake & dilution. Float ring ensures buoyancy and vertical orientation.
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EASY TO USE
Screw-on cap and pipette provides easy and safe sample loading and in-process testing with no dangerous needles.
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TOTAL SAMPLE RECOVERY
Cylindrical shape provides open access for 95-98% sample volume recovery.
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BROAD MWCO RANGE
9 MWCOs from 0.1 - 1,000 kD for all dialysis applications from small peptides to large nanoparticles.
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HIGH PURITY
Achieve 98% sample purity with Biotech CE membrane, no heavy metal and sulfides.
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FEATURED APPLICATION
Drug Dissolution: Controlled release for dose determination. USP Apparatus 2 and 4 compatible.

SpectraPor® Tube-A-Lyzer® dialysis device

Choose the right membranes by checking 
the Chemical Compatibility Table and the Pore Size Chart.

Do you have any questions or do you want to get a quote?
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Elliot Schupak
European Director
Mobile: +33 (0) 768 490 441
Telephone: +41 (0) 27 329 09 36
e.schupak@defimedica.com
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